Suppressor T cells against delayed type hypersensitivity to Mycobacterium intracellulare.

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Two types of suppressor T cells that inhibit delayed-type hypersensitivity to Mycobacterium intracellulare in mice.

Mycobacterium intracellulare Mino grows progressively in the organs of C57BL/6 mice. When C57BL/6 mice were injected with strain Mino, very weak or almost no delayed-type hypersensitivity (DTH) to the specific antigen, M. intracellulare purified protein derivative, was observed. The DTH response was enhanced by cyclophosphamide pretreatment, indicating that some suppression mechanism(s) might b...

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Specific suppressor T cells for delayed-type hypersensitivity in susceptible mice immunized against cutaneous leishmaniasis.

BALB/c mice injected intravenously with 10(6) or higher doses of formaldehyde-fixed promastigotes (ffp) of Leishmania major developed significantly lower levels of delayed-type hypersensitivity (DTH) compared with uninjected control mice when they were subsequently immunized intradermally with ffp. The suppression of DTH was antigen specific and was also inducible with lethally irradiated proma...

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Delayed-type hypersensitivity to influenza virus. Induction of antigen- specific suppressor T cells for delayed-type hypersensitivity to hemagglutinin during influenza virus infection in mice

Mice infected with A/England/939/69 X A/Puerto Rico/8/34 (Rec 31) influenza virus by aerosol develop significantly lower levels of delayed-type hypersensitivity (DTH) to A/Hong Kong/1/68 X A/Puerto Rico/8/34/ (X31) virus compared to uninfected mice. The suppression of DTH to the hemagglutinin appears to be mediated by suppressor T cells which carry Lyt-1 membrane antigen marker, and not by sy s...

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Genetic control of delayed type hypersensitivity to Mycobacterium leprae antigen.

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Suppressor factor from a T cell hybrid inhibits delayed-type hypersensitivity responses to azobenzenearsonate.

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ژورنال

عنوان ژورنال: Journal of Nippon Medical School

سال: 1989

ISSN: 0048-0444,1884-0108

DOI: 10.1272/jnms1923.56.187